David turned professional in 2000 and in his first match on the ATP tour he was beaten in a very close match in three sets by former number one, Jim Courier. The following year, he played his first final in the ATP Tour in Palermo and ended the year in the ATP top 50.
The 2002 season confirmed that David was one of the best players in the circuit. He surprised the world when he reached the Wimbledon final, the only Argentine player to ever achieve that, where was defeated by Lleyton Hewitt, who was the world's No. 1 at that moment. David won his first tournaments in the circuit, in Estoril and Basilea, and finished the year among the top 12 in the world ranking.
In 2003, David reached the semi-finals in the US Open, losing to Andy Roddick in a closely fought match. He made his run to the quarter-finals in the Australian Grand Slam, the finals in the Basilea tournament and the semi-finals in the Hamburg Master Series. Because of his great performance, he held the No. 8 ranking when the season came to a close and qualified for the first time in his career for the Masters Cup.
He suffered a series of injuries in 2004 which led to him to a year or erratic performances. However, this did not prevent him from remaining at the top of the rankings. He reached the semi-finals at Roland Garros where he lost to his fellow compatriot Gaston Gaudio, and also made it to the quarter-finals in Australia. He finished the year ranked No. 9 in the world.

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Apart from tennis, David has other hobbies that he loves. Rally car racing is one of those passions that he has had since he was a child and it is one that he shares with his family and friends. This love for Rally led him and his friend Marcos Ligato, a rally car driver, to launch the Tango Rally Team. His team competes in the World Rally in the production category and also in the Argentine Rally.
David often gets into racing cars and likes to feel the adrenaline of speed, leading him to debut as a driver in the Master Rally in Andalgala, Catamarca province (Argentina) in 2007.
He is also a soccer enthusiast, both on and off the field—he likes to play and is also a big fan of the River Plate team.
Everything that has to do with nature entices David. He loves to go fishing especially if he is with friends.
Adrenaline and adventure have led him to face new challenges in all kinds of activities. For example, he went bungee jumping in Vienna, leaping from the 152 meter high Danube Tower and swam with sharks in Melbourne, Australia.
Polo is another of his favorites and he closely follows La Dolfina polo team. Golf is one of the other activities that he enjoys and often plays.
Since he became widely known in the world sports, he has been encouraged to leave Unquillo and move to Buenos Aires. However, he has never accepted because what he values most is in his hometown—his family and friends with whom he finds the happiness, peace and love that he needs in his life.